Textbook of Clinical Embryology

-= Textbook of Clinical Embryology =-

Textbook of Clinical Embryology. Coward K., Wells D. (eds.). Cambridge University Press, 2013

 Textbook of Clinical Embryology

The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook - inspired by the postgraduate degree program at the University of Oxford - guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.


List of contributors

Section 1 Mammalian reproductive physiology

1 Sexual reproduction: an overview
2 Sexual development
3 The male reproductive tract and spermatogenesis
4 Female reproductive tract and oocyte development
5 Ovulation and regulation of the menstrual cycle
6 Key events in early oogenesis affecting oocyte competence in women
7 Regulation of gonadal function
8 Reproductive endocrinology
9 Reproductive immunology
10 Sperm biology and maturation
11 Fertilization and egg activation
12 Early embryogenesls
13 Human organogenesis

Section 2 Infertility

14 Global perspectives in reproductive health and fertility
15 Fertility control and contraception
16 Causes and investigations of male and female infertility
17 Treatment of male and female infertility
18 Social aspects of using reproductive technology

Section 3 Assisted Reproductive Technology (ART)

19 From Pythagoras and Aristotle to Boveri and Edwards: a history of clinical embryology and therapeutic IVF
20 Legal, ethical and regulatory aspects of Assisted Reproductive Technology (ART)
21 Quality management in assisted reproduction
22 Regulation of assisted conception in the UK

Section 4 ART: skills, techniques and present status

23 Fundamental laboratory skills for clinical embryologists
24 Semen analysis and preparation
25 Superovulation protocols
26 Intracytoplasmic sperm injection (ICSI)
27 Embryo culture
28 Embryo biopsy
29 In vitro maturation of oocytes
30 Morphological expressions of human egg and embryo quality
31 Cryopreservation in assisted reproduction
32 Reproductive surgery
33 Preimplantation genetic diagnosis
34 Preimplantation genetic screening
35 The biology and therapeutic potential of embryonic stem cells
36 Ethical considerations for clinical embryology